Removal of giant sternal tumors requires extensive resection of the anterior chest wall, and results in deformity and paradoxical movement. Pdf on may 1, 2014, somin hwang and others published chondromyxoid fibroma of the finger find, read and cite all the research you need on. Abstract chondromyxoid fibroma is a benign, although potentially aggressive tumor, with a cartilagelike matrix, accounting for approximately 1% of all bone. Chon dromyxoid fibroma is a rare tumor arising from cartilageforming. Jan 29, 2020 chondromyxoid fibroma like osteosarcoma cmfos is an exceedingly rare subtype of lowgrade central osteosarcoma lgco, accounting for up to 10% of cases and making it difficult to diagnose. Article information, pdf download for chondromyxoid fibroma of the. Ct scan shows large irregular osteolytic and expansile lesion in a rib. Get a printable copy pdf file of the complete article 647k, or click on a page image below to browse page by page.
Chondromyxoid fibroma cmf is one of the rarest of bone tumors, accounting for less than 1% of all bone tumors. Chondromyxoid fibromas cmfs are extremely rare, benign cartilaginous neoplasms that account for chondromyxoid fibroma cmf is a benign, locally aggressive tumor of cartilaginous origin and accounts for less than 0. Chondromyxoid fibroma cmf is a rare, benign bone tumor found most often in the bones of the legs, arms, feet, hands, fingers and toes. Computed tomography revealed an osteolytic lesion with. Concomitant lupus with features of scleroderma, castleman disease rheumatology case report. Bullous lesions in patient with lupus explore this issuefebruary 2016 her chest radiograph revealed no. This is an advanced case of a benign chondromyxoid fibroma. Males have a higher incidence, with no other demographic bias 3. Only 2 of the 50 chondromyxoid fibromas included in their study occurred in the skull. In 1948, the tumor was first described by jaffe and lichtenstein as a lesion derived from cartilageforming tissue and composed of various proportions of chondroid, fibrous, and myxoid tissues.
Chondromyxoid fibroma childrens hospital of philadelphia. Chondromyxoid ibroma is a very rare benign cartilaginous tumor representing less than 0. Save your office file as a pdf without needing additional software or addins. Chondromyxoid fibroma is a benign tumor of bone that is characterized by chondroid and myxoid differentiation and by ultrastructural and immunohistochemical evidence of chondral origin. A primary chondromyxoid fibroma cmf arising from sternum is quite uncommon tumor in thoracic surgery. It belongs to the group of benign cartilage tumours and has. Chondromyxoid fibroma cmf is a benign tumor of cartilagenous origin and rarest of all bone tumors. Primary chondromyxoid fibroma of the sternum is quite rare, with only six cases documented in the literature see table 1. Sep 23, 2016 chondromyxoid fibroma cmf is a benign, locally aggressive tumor of cartilaginous origin and accounts for less than 0. Pdf background several different strategies have been reported for the treatment of chondromyxoid fibromas, all with variable outcomes and. July 27, 2017 056 the tumor may be discovered incidentally during radiography 1.
Chondromyxoid fibroma cmf is a benign rare bone tumor of slowgrowing nature arising from chondroblastic derivation 14. The decisive role played by the radiologist in identifying the benign nature of the lesion is emphasized. We report a case of a 35yearold female with a 3 month history of lower back pain after sustaining a fall on her sacrumcoccyx presenting with a progressive complaint of localized lower back pain, occasional urinary retention without incontinence, gluteal hypesthesia, and. The treatment of the secondary abc is based on the appropriate treatment for the underlying tumor. Chondromyxoid fibroma of the jaws wiley online library. Chondromyxoid fibroma of frontal bone is a rare lesion. A rare case of juxtacortic chondromyxoid fibroma in proximal. Chondromyxoid fibroma cmf is a rarely encountered benign bone chondroid tumor. A special form is the keloid, which derives from hyperplastic growth of scars soft fibroma. Soni r, kapoor c, shah m, turakhiya j, golwala p 2016 chondromyxoid fibroma. Chondromyxoid fibroma of bone, a clinicopathologic study of thirtytwo cases. Chondromyxoid fibroma is a very rare benign cartilaginous tumor representing less than 0. The craniofacial region is affected in only 2% of cases.
Jan 08, 2015 chondromyxoid fibroma cmf is a rare, benign tumor of the bone that was described by jaffe and lichenstein in 1948. Eight new cases are added, 4 of which exhibited unusual size andor focal microscopic calcification, pathologic fracture, diaphyseal location. Smaller lesions are typically located in the cortex of long bones. Chondromyxoid fibroma is a tumor of the cartilage found between your bones. Nov 28, 2015 a primary chondromyxoid fibroma cmf arising from sternum is quite uncommon tumor in thoracic surgery. It is composed of a mixture of chondroid, myxoid, and fibrous tissues. Jaffe and lichtenstein first described the condition in 1943. Chondromyxoid fibroma is a benign but aggressive tumor occurring primarily in the first and second decades of life 42, but can appear as early as 3 years and as late as 79. Many programs, including microsoft word, have the ability to open and edit pdf files. Pdf chondromyxoid fibroma of the finger researchgate. Surgical management of a giant sternal chondromyxoid fibroma.
To present a case of chondromyxoid fibroma of the nasal bone and discuss its presentation. The hard fibroma fibroma durum consists of many fibres and few cells, e. An adult male patient at the age of 28 suffered a fracture of the lateral malleolus due to an eccentric, lytic, lobular lesion in the epiphysis, during a basketball match. Plain skull films showed a round radiolucent mass with a sclerotic margin.
Chondromyxoid fibroma of the maxillofacial region is typically seen in. Mri of chondromyxoid fibroma article pdf available in acta radiologica 528. Chondromyxoid fibroma of the frontal bone tatsuo morimura, 12 atsuhisa nakano, 1 tsuyoshi matsumoto, 1 and eiichi tani1 summary. Chondromyxoid fibroma cmf was first described by jaffe and lichtenstein 1. Chondromyxoid fibroma of the nasal bone with extension into the frontal and ethmoidal sinuses. Chondromyxoid fibroma cmf is a benign, locally aggressive tumor of cartilaginous origin and accounts for less than 0. To our knowledge, this is the first reportable case of cmp presenting with undifferentiated connective tissue.
Chondromyxoid fibroma cmf is a rare benign bony tumour. Chondromyxoid fibroma arising in a flat bone may show irregular contours with osteolysis and bone expansion fig. Sep 24, 2018 chondromyxoid fibroma cmf is a rare, slowgrowing, benign bone tumor of chondroblastic derivation. The soft fibroma fibroma molle or fibroma with a shaft acrochordon, skin tag, fibroma pendulans consist of many. Chondromyxoid fibroma typically occurs in children and young adults between the ages of 10 and 30, and accounts for less than 1 percent of all bone tumors. Radiological evaluation of a chondromyxoid fibroma heighpubs. Chondromyxoid fibroma cmf is a rare benign bone neoplasm which often occurs in the lower extremities. A 16yearold asian male presented to the hospital 12 months ago with bilateral diplopia involving right visual fields, intermittent headaches, and. Dec 01, 2019 save your office file as a pdf without needing additional software or addins.
Chondromyxoid fibroma, which is a relatively late addition to the family of bone tumors, is a rare lesion that occurs in less than 1% of bone tumors and tumorlike lesions. Rarer locations include the fibula, scapula, vertebrae and ribs 3. However, the case presented here is an extremely rare case as the tumor affected the middle and upper segment of the humerus. Tinu syndrome with concomitant synovitis rheumatology case report. Chondromyxoid fibroma is a benign tumor composed of spindle or stellate cells forming lobules and with abundant myxoid andor. The possibility of chondromyxoid fibroma should always be considered when a focal bone lesion is evaluated that has geographic bone destruction, a sclerotic rim, lobulated margins, and septation. Treatment for cmf requires surgery to remove the tumor. Chondromyxoid fibromas cmfs are extremely rare, benign cartilaginous neoplasms that account for chondromyxoid fibroma but no cartilaginous areas, usually older adults.
Learn more about how this cancer forms, is treated, and the prognosis. The differential diagnosis included the chondroblastoma, the aneurysmal cyst and. The lesion is never purely epiphyseal, but may extend into the subchondral b. Chondromyxoid fibroma cmf is a rare benign neoplasm of cartilaginous origin and represents less than 1% of all primary tumors of bone. A rare case of juxtacortic chondromyxoid fibroma in. It is associated with high local recurrence rates with a small risk chondromyxoid fibroma cmf is one of the rarest benign tumors of cartilaginous origin. A 40yearold female presented a progressively enlarging mass of her anterior chest wall. Little is known about the radiological and histological presentation of cmf in the sellar region patient concerns. More than half of the cases develop in the second and third decades of life. Cmf is most often found in the long tubular bones, especially the tibia and femur near the knee joint. Chondromyxoid fibroma definition of chondromyxoid fibroma. Radiological presentation of chondromyxoid fibroma in the. Complete local excision with tumorfree margins avoids the recurrence of cmf, the underlying tumor in this case report. Chondromyxoid fibroma is a benign tumor composed of spindle or stellate cells forming lobules and with abundant myxoid andor chondroid intercellular material.
It was dense on plain ct scan and showed no convincing contrast enhancement. Surgical management of a giant sternal chondromyxoid. Chondromyxoid fibroma of bone, with emphasis on its morphological relationship to benign chondroblastoma. Chondromyxoid fibroma cmf is one of the rarest benign tumors of cartilaginous origin.
It is a benign noncancerous tumor that most often develops in older children and young adults under 30 years of age. Radiological evaluation of a chondromyxoid fibroma published. Chondroblastoma and chondromyxoid fibroma abstract chondroblastoma and chondromyxoid. It usually affects young people between the ages of 10 and 30 years old. The back pain is suggestive of an underlying inflammatory condition, such as seronegative spondyloarthropathy, likely ankylosing spondylitis. A study of 76 chondromyxoid fibromas affirms that it is a benign tumor, ap parently of cartilaginous derivation, that is most likely to occur in adolesrents. We report a case of a 35yearold female with a 3 month history of lower back pain after sustaining a fall on her sacrumcoccyx presenting with a progressive complaint of localized lower back pain, occasional urinary retention without incontinence. Most cases of cmf occur in the metaphysis of tubular bones of the lower extremity. Chondromyxoid fibroma with secondary aneurysmal bone. Most cases are characterised by grm1 gene fusion or promoter swapping. Chondromyxoid fibroma constitutes a rare benign tumor of the bones, which has a potential of regional enlargement towards the local tissues. Chondroblastoma, a destructive lesion with a thin radiodense border, is usually seen in the epiphysis of long bones. Chondromyxoid fibroma of the petrygopalatine space the.
Bullous lesions in patient with lupus explore this issuefebruary 2016 her chest radiograph revealed no infiltrates. Chondromyxoid fibroma cmf is a relatively uncommon benign bone. Chondromyxoid fibroma is a rare benign tumor that usually occurs in the long bones and rarely affects the sinonasal region. It accounts for less than 1% of all bone tumors and approximately 95% of these cases are seen in metaphysis of long bone. Chondromyxoid fibroma cmf is an extremely rare, benign cartilaginous tumor that makes up case description. Its treatment is a controversial issue due to its lowgrade classification and actual high. It permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Jan 24, 2016 chondromyxoid fibroma cmf is a rare entity, representing chondromyxoid fibroma cmf is a rare benign neoplasm of cartilaginous origin and represents less than 1% of all primary tumors of bone.
Chondromyxoid fibroma cmf is a benign cartilaginous neoplasm first distinguished from other cartilaginous tumors by jaffe and lichenstein in 1948. This article is from archives of plastic surgery, volume 41. Tumors located in the distal extremities such as the hands or feet may only present clinically with signs of painless swelling 5. The most commonly affected area is the metaphysial region of the proximal tibia and the distal femur 2. Juxtacortical chondromyxoid fibroma of tibia bjstr. Foot, chondromyxoid fibroma, cartilaginous tumor, lytic lesion toe, curettage this is an open access article distributed under the terms of the creative commons attribution license. The diagnosis of cmf depends upon its characteristic histological appearance like a lobular pattern with stellateshaped cells in a myxoid or.
Chondromyxoid fibroma cmf is a rare entity, representing file. All intext references underlined in blue are added to the original document and are linked to publications on researchgate, letting you access and read them immediately. Chondromyxoid fibroma may occur anywhere in the skeleton, but almost half of the cases occur around the knee. Chondromyxoid fibroma, pediatric orthopaedic society of north america posna 1 tower ln, suite 2410 oakbrook terrace, il 60181 p. Cmfos is frequently misdiagnosed on a radiological examination and biopsy, even after the initial operation. Chondromyxoid fibroma of the rib initially seen as a. Open access publication chondromyxoid fibroma of the foot. Both clinically and histologically, it is a difficult diagnosis and can be confused with malignant lesions.
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